14th CCS National Conference on Analytical Chemistry (Shenzhen University)

[Poster 1]
◆ Title: Qualitative Method for Polymeric HALS by In-Source CID
Presenter: ○Xi Li¹, Naru Higeta¹, Keiko Matsuda¹
　　　　　　　　 1 Toray Research Center, Inc.
Date: November 3~5, 2023
Venue: Shenzhen University
Presentation Details:
Polymeric hindered amine light stabilizers (HALS) are essential for outdoor polymer materials but difficult to qualify. We envisioned that if in-source CID (IS-CID) was used in the LC/MS to dissociate polymeric HALS to produce low molecular weight fragment ions, it would be possible to achieve qualitative analysis beyond the detection mass range. In this study, the feasibility of IS-CID combined with ESI-MS for the characterization of polymeric HALS was investigated using three standard samples. Meanwhile, to verify the practicality of this method, one commercial paint was selected and extracted with suitable pretreatment to obtain the additives. The conventional LC/MS/MS and LC/IS-CID-MS/MS were carried out respectively. As a result, the unknown polymeric HALS in the commercial paint was successfully qualified only by LC/ IS-CID-MS/MS.

[Poster 2]
◆ Title: Determination and Gas-phase Stability Evaluation of Metal Complexes by NanoESI-MSMS
Presenter: ○Xi Li¹, Keisuke Sawada¹, Takahiro Shioji¹
　　　　　　　　1 Toray Research Center, Inc.
Date: November 3~5, 2023
Venue: Shenzhen University
Presentation Details:
Mass spectrometry (MS) is a common method for studying metal complexes. However, it is challenging to detect some labile complexes with the current approach. In this study, an extremely soft nanoelectrospray ionization technique combined with MS (nanoESI-MS) was used to successfully detect Zn(BP)2, Fe(acac)3 and Sn(EH)2, which is difficult to achieve using conventional ESI-MS, represents the first application of nanoESI-MS to detect metal complexes. Furthermore, the retention of metal complexes in their native structure determines the ability to function stably in product performance. We successfully evaluated the gas-phase stability of alkylamine-Ag+ complexes using nanoESI combined with collision-induced dissociation tandem mass spectrometry (CID-MS/MS) and confirmed the validity by quantum chemical calculations. In addition, nanoESI-MS/MS can also evaluate the interaction between associated ions. Therefore, it is expected to play an important role in material selection for industrial production.

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